產(chǎn)品屬性:
產(chǎn)品名稱 | p-MPPI hydrochloride |
規(guī)格 | 10mM*1 mL in DMSO、10mg、25mg、50mg、100mg |
貨號(hào) | EY-01Y16215 |
Cas No.: 220643-77-6
別名: N/A
化學(xué)名: N/A
分子式: C25H28ClIN4O2
分子量: 578.87
溶解度: DMSO: 17.86 mg/mL (30.85 mM)
儲(chǔ)存條件: 4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
p-MPPI hydrochloride is a selective 5-HT1A receptor antagonist with high affinity for 5-HT1A receptors. p-MPPI hydrochloride can crosses the blood-brain barrier, and has clear antidepressant and anxiolytic-like effects[1][2].p-MPPI hydrochloride has no agonist activity in both in vitro and in vivo tests of pre- and post-synaptic 5-HT1A receptor activity[1].p-MPPI hydrochloride (0.5-4.5 mg/kg; i.p.) shows anxiolytic-like profile in the murine elevated plus-maze[2].
特別提醒公司產(chǎn)品僅供科研使用