產(chǎn)品屬性：
產(chǎn)品名稱 | p32 Inhibitor M36 |
規(guī)格 | 1mg、5mg |
貨號(hào) | EY-01Y15807 |
Cas No.: 802555-85-7
別名: N/A
化學(xué)名: N/A
分子式: C23H28N8O2
分子量: 448.52
溶解度: DMSO: 5 mg/mL (11.15 mM; ultrasonic and warming and heat to 80°C)
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
p32 inhibitor M36 (M36) is a p32 mitochondrial protein inhibitor, which binds directly to p32 and inhibits p32 association with LyP-1[1].p32[1]p32 Inhibitor M36 inhibits SF188 glioma cells proliferation (IC50 of 77.9 μM in complete media) and is much more potent under low glucose conditions with an IC50 of 7.3 μM[1]. p32 Inhibitor M36 is selective for p32 overexpressing cells[1].p32 Inhibitor M36 is also a potent inhibitor of patient-derived neurospheres with an IC50 of 2.8 μM[1].[1]. Yenugonda V,et al. A novel small molecule inhibitor of p32 mitochondrial protein overexpressed in glioma. J Transl Med. 2017 Oct 18;15(1):210.
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