產(chǎn)品屬性:
產(chǎn)品名稱 | cis-Resveratrol |
規(guī)格 | 5mg、10mg、50mg、100mg |
貨號 | EY-01Y9764 |
Cas No.: 61434-67-1
別名: (Z)-Resveratrol
化學(xué)名: 5[(1Z)-2-(4-hydroxyphenyl)ethenyl]-1,3-benzenediol
分子式: C14H12O3
分子量: 228.2
溶解度: 50mg/mL in DMSO, or in DMF
儲存條件: Store at -80°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
Resveratrol is a potent phenolic antioxidant found in grapes, red wine, and various berries that also has antiproliferative and anti-inflammatory activity. cis-Resveratrol is the double bond isomer of trans-resveratrol, the more often studied and naturally abundant of the two resveratrol isomers. cis-Resveratrol exhibits antioxidant activity in the μM range similar to that observed with trans-resveratrol. It blocks production of reactive oxygen species (ROS) by inhibition of NAD(P)H oxidase and also inhibits production of nitric oxide. At a concentration of 100 μM, cis-resveratrol significantly inhibits the expression of genes related to the Rel/NF-κB/IκB family, adhesion molecules, and acute-phase proteins in LPS and INF-γ-stimulated murine peritoneal macrophages. cis-Resveratrol inhibits uptake of noradrenaline and 5-HT by synaptosomes from rat brain with IC50 values of 79 and 51 μM, respectively. It also inhibits human monoamine oxidase-A (MOA-A) and MOA-B with IC50 values of 25 and 61 μM, respectively, which is similar to, but slightly less effective than, values obtained with trans-resveratrol."
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