產(chǎn)品屬性：
產(chǎn)品名稱 | uPSEM 817 tartrate |
規(guī)格 | 5 mg、25 mg |
貨號 | EY-01Y9598 |
Cas No.: 2341833-14-3
別名: N/A
化學(xué)名: N/A
分子式: C16H19N3O.C4H6O6
分子量: 419.43
溶解度: Soluble in DMSO
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Selective ultrapotent PSEM (uPSEM) agonist for α7L131G,Q139L,Y217F-GlyR (PSAM4-GlyR) and PSAM4-5-HT3 chimeric ion channel agonist (EC50 values are 0.3 and 0.5 nM, respectively). Suppresses firing of layer 2/3 cortical neurons expressing PSAM4-GlyR in brain slices. Increases contralateral rotation in mice expressing PSAM4-GlyR unilaterally in the substantia nigra reticulata (LED 0.1 mg/kg).Magnus et al (2019) Ultrapotent chemogenetics for research and potential clinical applications. Science 364 PMID:30872534
特別提醒公司產(chǎn)品僅供科研使用
